Welcome to the 16th International Symposium on Variants in the Genome, taking place from 20 - 23 May 2026, in the beautiful city of Leuven, Belgium. We are thrilled to invite you back for this in-person event.

This biennial conference, formerly known as the Mutation Detection meeting series, will delve into the latest advancements in scanning, sequencing, databasing, and bioinformatics analysis of genetic variants in DNA, RNA, and protein. As technology rapidly evolves, understanding the impact of these variants on individual health is becoming increasingly vital, transforming how we interpret genomic data. This year's symposium will place special emphasis on the methodologies and capabilities for functional testing and classification of genomic variants associated with disease.

Renowned scientists from around the globe will present their groundbreaking research during plenary sessions, alongside speakers selected from submitted abstracts through a rigorous peer-review process. 

ISV2026 serves as an excellent platform for knowledge-sharing and networking with international leaders in human genetics. We encourage you to submit your abstracts promptly and to join us in Leuven for this dynamic and enriching experience.

We look forward to welcoming you in 2026!

Mark your calendars!

• Beyond the Code: Non-Coding Variation & Gene Regulation
• The Next Frontier: Sequencing Technologies & Genomic Insights
• From Variants to Patients: Clinical Applications & Diagnostics
• Beyond Cancer: Somatic Variation in Health & Disease
• AI & Functional Genomics: Unlocking Variant Impact
• Large-Scale Projects: Building the Future of Genomic Medicine
• Beyond Discovery: Frontiers of Application in Genomic Research
• Emerging & Cutting-Edge Topics in Variant Research

We warmly invite you to submit an abstract to present your research at ISV2026. Abstract submissions will open 4th August 2025, and we encourage contributions from researchers at all career stages.

Presentation Formats:

• Oral Presentations: Share your latest findings with the full audience.
• Poster Presentations: Engage in in-depth discussions in an informal setting.

Presenting at ISV2026 offers excellent visibility and the chance to contribute directly to the scientific conversation shaping our understanding of genomic variation.

20th - 23rd May 2026

The Irish College

Leuven

Belgium

ISV2026 will be held at the historic Irish College, a beautifully restored heritage venue in the heart of Leuven, Belgium. This unique setting combines modern conference facilities with the charm and character of its 17th-century origins. The College offers bright, spacious meeting rooms and tranquil gardens, providing an inspiring environment for scientific exchange.

Accomodation booking at The Irish College and other nearby hotels will open on 4th August 2025. 
 

Leuven is easily accessible being only 20 mins from Brussels airport (BRU) by train. View our travel information here.

Leuven is a vibrant university city renowned for its rich history, lively culture, and welcoming atmosphere. Home to KU Leuven, one of Europe’s leading research universities, the city offers a perfect mix of historic charm and modern innovation. Stroll through cobblestone streets, visit the iconic Town Hall and University Library, or enjoy a taste of Belgian beer culture at one of Leuven’s many bars and cafés. Leuven’s central location also makes it an ideal base for exploring nearby cities such as Brussels, Antwerp, and Bruges.

• Stay at the forefront of research into genetic variation and its clinical significance.
• Gain insights into new technologies, analytical approaches, and interpretation frameworks that are shaping the future of genomic medicine.
• Engage with renowned keynote speakers (to be announced), who will present groundbreaking research and perspectives.
• Present your own work to a global audience through oral or poster presentations.
• Take part in lively discussions that address key challenges.
• Expand your professional network, building new collaborations and reconnecting with colleagues from around the world.

©2025 International Symposium on Variants in the Genome 2026. All rights reserved.